Enhanced contractility and myosin phosphorylation induced by Ca2+-independent MLCK activity in hypertensive rats

Aims The role of Ca2+ sensitization induced by a Ca2+-independent myosin light chain kinase (MLCK) in hypertension has not been determined. The aim of this study was to clarify the role of possible Ca2+-independent MLCK activity in hypertension. Methods and results We compared increases in contracti...

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Veröffentlicht in:Cardiovascular research 2011-07, Vol.91 (1), p.162-170
Hauptverfasser: Cho, Young-Eun, Ahn, Duck-Sun, Morgan, Kathleen G., Lee, Young-Ho
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Sprache:eng
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