Pattern and timing of gene duplication in animal genomes

Duplication of genes, giving rise to multigene families, has been a characteristic feature of the evolution of eukaryotic genomes. In the case of vertebrates, it has been proposed that an increase in gene number resulted from two rounds of duplication of the entire genome by polyploidization (the 2R...

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Veröffentlicht in:	Genome research 2001-11, Vol.11 (11), p.1842-1847
Hauptverfasser:	Friedman, R, Hughes, A L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Caenorhabditis elegans - genetics Drosophila melanogaster Drosophila melanogaster - genetics duplication Evolution, Molecular Gene Duplication Genes - genetics Genes, Helminth - genetics Genes, Insect - genetics Genome Genome, Human Humans Letter Multigene Family Phylogeny
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