Shotgun optical maps of the whole Escherichia coli O157:H7 genome

We have constructed NheI and XhoI optical maps of Escherichia coli O157:H7 solely from genomic DNA molecules to provide a uniquely valuable scaffold for contig closure and sequence validation. E. coli O157:H7 is a common pathogen found in contaminated food and water. Our approach obviated the need f...

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Veröffentlicht in:	Genome research 2001-09, Vol.11 (9), p.1584-1593
Hauptverfasser:	Lim, A, Dimalanta, E T, Potamousis, K D, Yen, G, Apodoca, J, Tao, C, Lin, J, Qi, R, Skiadas, J, Ramanathan, A, Perna, N T, Plunkett, 3rd, G, Burland, V, Mau, B, Hackett, J, Blattner, F R, Anantharaman, T S, Mishra, B, Schwartz, D C
Format:	Artikel
Sprache:	eng
Schlagworte:	Contig Mapping - methods Escherichia coli Escherichia coli O157 - genetics Genome, Bacterial Methods Restriction Mapping - methods Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
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