A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

We created a whole-mount in situ hybridization (WISH) database, termed EMBRYS, containing expression data of 1520 transcription factors and cofactors expressed in E9.5, E10.5, and E11.5 mouse embryos—a highly dynamic stage of skeletal myogenesis. This approach implicated 43 genes in regulation of em...

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Veröffentlicht in:	Developmental cell 2009-12, Vol.17 (6), p.836-848
Hauptverfasser:	Yokoyama, Shigetoshi, Ito, Yoshiaki, Ueno-Kudoh, Hiroe, Shimizu, Hirohito, Uchibe, Kenta, Albini, Sonia, Mitsuoka, Kazuhiko, Miyaki, Shigeru, Kiso, Minako, Nagai, Akane, Hikata, Tomohiro, Osada, Tadahiro, Fukuda, Noritsugu, Yamashita, Satoshi, Harada, Daisuke, Mezzano, Valeria, Kasai, Masataka, Puri, Pier Lorenzo, Hayashizaki, Yoshihide, Okado, Haruo, Hashimoto, Megumi, Asahara, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell differentiation, maturation, development, hematopoiesis Cell physiology Cofactors Computer programs Data processing DEVBIO DNA microarrays Embryos Fibroblasts Fundamental and applied biological sciences. Psychology Gene Knockdown Techniques Gene Knockout Techniques Gene regulation Gene Regulatory Networks Genomes Inhibitor of Differentiation Protein 2 - metabolism Inhibitor of Differentiation Proteins - metabolism Mice Molecular and cellular biology Molecular genetics Muscle Development Muscle regulatory factor Muscle, Skeletal - embryology MyoD protein myogenesis Myogenic Regulatory Factors - genetics Repressor Proteins - metabolism Repressors Transcription Transcription factors Transcription. Transcription factor. Splicing. Rna processing Transfection Zinc finger proteins
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