Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver
Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF. Retrospective analysis records of 1...
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Veröffentlicht in: | Indian journal of nuclear medicine 2010-10, Vol.25 (4), p.139-142 |
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container_title | Indian journal of nuclear medicine |
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creator | Chakraborty, Dhritiman Sunil, Hejjaji Venkataramarao Mittal, Bhagwant Rai Bhattacharya, Anish Singh, Baljinder Chawla, Yogesh |
description | Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value |
doi_str_mv | 10.4103/0972-3919.78247 |
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Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value<0.0001).
Tc99m sulfur colloid liver scan is a non-invasive procedure having a useful adjunctive role in clinical differentiation of cirrhosis from NCPF.</description><identifier>ISSN: 0972-3919</identifier><identifier>EISSN: 0974-0244</identifier><identifier>DOI: 10.4103/0972-3919.78247</identifier><identifier>PMID: 21713221</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Bone marrow ; Care and treatment ; Colloids in medicine ; Diagnosis ; Fibrosis ; Liver cirrhosis ; Medical imaging ; Nuclear medicine ; Original ; Physiological aspects ; Spleen ; Tissues</subject><ispartof>Indian journal of nuclear medicine, 2010-10, Vol.25 (4), p.139-142</ispartof><rights>COPYRIGHT 2010 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt Ltd Oct 2010</rights><rights>Indian Journal of Nuclear Medicine 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c478t-5577e5c1a561a9a290fb211bdef4900ed55bd53ca4929ffedf34fba5336619663</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109819/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109819/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21713221$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chakraborty, Dhritiman</creatorcontrib><creatorcontrib>Sunil, Hejjaji Venkataramarao</creatorcontrib><creatorcontrib>Mittal, Bhagwant Rai</creatorcontrib><creatorcontrib>Bhattacharya, Anish</creatorcontrib><creatorcontrib>Singh, Baljinder</creatorcontrib><creatorcontrib>Chawla, Yogesh</creatorcontrib><title>Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver</title><title>Indian journal of nuclear medicine</title><addtitle>Indian J Nucl Med</addtitle><description>Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value<0.0001).
Tc99m sulfur colloid liver scan is a non-invasive procedure having a useful adjunctive role in clinical differentiation of cirrhosis from NCPF.</description><subject>Bone marrow</subject><subject>Care and treatment</subject><subject>Colloids in medicine</subject><subject>Diagnosis</subject><subject>Fibrosis</subject><subject>Liver cirrhosis</subject><subject>Medical imaging</subject><subject>Nuclear medicine</subject><subject>Original</subject><subject>Physiological aspects</subject><subject>Spleen</subject><subject>Tissues</subject><issn>0972-3919</issn><issn>0974-0244</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkktrHiEUhofS0lzadXdFWkhXk3h33BRC6CUQKJR0LY6j3xgc_aozgfz7Opk0JFmp5zy-59o0HxA8pQiSMygFbolE8lR0mIpXzWG10BZiSl_f3zfvQXNUyg2EnArO3zYHGAlEMEaHTfqdggXJgWsj5QTKEtySgUkhJD-AYnyc_S7r_XgHfASDd85mW2169nEHYoqt8TmPafYG7FOedQDO9zkVX4DLaQKbe30Gf2vzu-aN06HY9w_ncfPn-7fri5_t1a8flxfnV62hoptbxoSwzCDNONJSYwldjxHqB-uohNAOjPUDI0ZTiWXNaXCEul4zQjhHknNy3HzddPdLP9nB1JyzDmqf_aTznUraq-ee6Ee1S7eKICg7JKvAlweBnP4utsxq8sXYEHS0aSmqExRLgSSr5KcX5E1acqzVqY5DiTsuVujzBu10sMpHl2pUs0qqc8wIFp2kuFInT6jR6jCPJYVl9imW5-DZBpra6pKte6wMQbVuhlpnr9bZq_vNqD8-Pm3II_9_Fcg_AwG0UQ</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Chakraborty, Dhritiman</creator><creator>Sunil, Hejjaji Venkataramarao</creator><creator>Mittal, Bhagwant Rai</creator><creator>Bhattacharya, Anish</creator><creator>Singh, Baljinder</creator><creator>Chawla, Yogesh</creator><general>Medknow Publications and Media Pvt. 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Sunil, Hejjaji Venkataramarao ; Mittal, Bhagwant Rai ; Bhattacharya, Anish ; Singh, Baljinder ; Chawla, Yogesh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-5577e5c1a561a9a290fb211bdef4900ed55bd53ca4929ffedf34fba5336619663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Bone marrow</topic><topic>Care and treatment</topic><topic>Colloids in medicine</topic><topic>Diagnosis</topic><topic>Fibrosis</topic><topic>Liver cirrhosis</topic><topic>Medical imaging</topic><topic>Nuclear medicine</topic><topic>Original</topic><topic>Physiological aspects</topic><topic>Spleen</topic><topic>Tissues</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chakraborty, Dhritiman</creatorcontrib><creatorcontrib>Sunil, Hejjaji Venkataramarao</creatorcontrib><creatorcontrib>Mittal, Bhagwant Rai</creatorcontrib><creatorcontrib>Bhattacharya, Anish</creatorcontrib><creatorcontrib>Singh, Baljinder</creatorcontrib><creatorcontrib>Chawla, Yogesh</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Research Library China</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chakraborty, Dhritiman</au><au>Sunil, Hejjaji Venkataramarao</au><au>Mittal, Bhagwant Rai</au><au>Bhattacharya, Anish</au><au>Singh, Baljinder</au><au>Chawla, Yogesh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver</atitle><jtitle>Indian journal of nuclear medicine</jtitle><addtitle>Indian J Nucl Med</addtitle><date>2010-10-01</date><risdate>2010</risdate><volume>25</volume><issue>4</issue><spage>139</spage><epage>142</epage><pages>139-142</pages><issn>0972-3919</issn><eissn>0974-0244</eissn><abstract>Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs.
Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value<0.0001).
Tc99m sulfur colloid liver scan is a non-invasive procedure having a useful adjunctive role in clinical differentiation of cirrhosis from NCPF.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>21713221</pmid><doi>10.4103/0972-3919.78247</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Bone marrow Care and treatment Colloids in medicine Diagnosis Fibrosis Liver cirrhosis Medical imaging Nuclear medicine Original Physiological aspects Spleen Tissues |
title | Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver |
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