Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver

Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF. Retrospective analysis records of 1...

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Veröffentlicht in:Indian journal of nuclear medicine 2010-10, Vol.25 (4), p.139-142
Hauptverfasser: Chakraborty, Dhritiman, Sunil, Hejjaji Venkataramarao, Mittal, Bhagwant Rai, Bhattacharya, Anish, Singh, Baljinder, Chawla, Yogesh
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container_end_page 142
container_issue 4
container_start_page 139
container_title Indian journal of nuclear medicine
container_volume 25
creator Chakraborty, Dhritiman
Sunil, Hejjaji Venkataramarao
Mittal, Bhagwant Rai
Bhattacharya, Anish
Singh, Baljinder
Chawla, Yogesh
description Two most important causes of portal hypertension are cirrhosis of liver and non-cirrhotic portal fibrosis (NCPF). The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF. Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs. Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs. Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value
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The purpose of this study was to assess the scintigraphic appearances of Tc99m sulfur colloid liver scan in differentiating liver cirrhosis from NCPF. Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs. Retrospective analysis records of 146 patients (91 male and 55 female) with diffuse hepatocellular disease was done for liver size, liver uptake, spleen size, spleen uptake, colloid shift to bone marrow and lungs. Cirrhotic livers showed patchy and lower uptake than NCPF (59% vs. 20%, P-value 0.041). Spleen size was significantly increased in NCPF compared to cirrhosis (100% vs. 67%, P-value 0.0137). Significant colloid shift to bone marrow was noted in cirrhosis (84% vs. 7%, P-value&lt;0.0001). Tc99m sulfur colloid liver scan is a non-invasive procedure having a useful adjunctive role in clinical differentiation of cirrhosis from NCPF.</description><identifier>ISSN: 0972-3919</identifier><identifier>EISSN: 0974-0244</identifier><identifier>DOI: 10.4103/0972-3919.78247</identifier><identifier>PMID: 21713221</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Bone marrow ; Care and treatment ; Colloids in medicine ; Diagnosis ; Fibrosis ; Liver cirrhosis ; Medical imaging ; Nuclear medicine ; Original ; Physiological aspects ; Spleen ; Tissues</subject><ispartof>Indian journal of nuclear medicine, 2010-10, Vol.25 (4), p.139-142</ispartof><rights>COPYRIGHT 2010 Medknow Publications and Media Pvt. 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source Medknow Open Access Medical Journals; PubMed Central; Alma/SFX Local Collection; PubMed Central Open Access
subjects Bone marrow
Care and treatment
Colloids in medicine
Diagnosis
Fibrosis
Liver cirrhosis
Medical imaging
Nuclear medicine
Original
Physiological aspects
Spleen
Tissues
title Role of Tc99m sulfur colloid scintigraphy in differentiating non-cirrhotic portal fibrosis from cirrhosis liver
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