A comparative immunofluorescence analysis of three clinical-stage antibodies in head and neck cancer

The antibody-based targeted delivery of bioactive molecules to tumour vasculature is an attractive avenue to concentrate therapeutic agents at cancer sites, while sparing normal organs. L19, F8 and F16 are three fully human monoclonal antibodies, specific to splice isoforms of fibronectin and tenasc...

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Veröffentlicht in:	Head & neck oncology 2011-05, Vol.3 (1), p.25-25, Article 25
Hauptverfasser:	Schwager, Kathrin, Villa, Alessandra, Rösli, Christoph, Neri, Dario, Rösli-Khabas, Maria, Moser, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Antibodies Antibodies - analysis Antibodies - metabolism Antibodies - therapeutic use Antibody Affinity Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Care and treatment Clinical trials Comparative analysis Derivatives Fibronectins Fluorescent Antibody Technique Head & neck cancer Head and neck cancer Head and Neck Neoplasms - immunology Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Health aspects Hospitals Humans Immunoconjugates - therapeutic use Immunofluorescence Immunohistochemistry - methods Immunotherapy - methods Larynx Neoplasm Metastasis Otolaryngology Physiological aspects Viral antibodies
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