Fluorescence polarization in homogeneous nucleic acid analysis

A new method for DNA diagnostics based on template-directed primer extension and detection by fluorescence polarization is described. In this method, amplified genomic DNA containing a polymorphic locus is incubated with oligonucleotide primers (designed to hybridize to the DNA template adjacent to...

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Veröffentlicht in:	Genome research 1999-05, Vol.9 (5), p.492-498
Hauptverfasser:	Chen, X, Levine, L, Kwok, P Y
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - analysis DNA - genetics Fluorescence Polarization - methods Genotype Methods Polymorphism, Genetic - genetics Sequence Analysis, DNA - methods Sequence Homology, Nucleic Acid
Online-Zugang:	Volltext
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