Age-related alterations in retinal neurovascular and inflammatory transcripts

Vision loss is one of the most common complications of aging, even in individuals with no diagnosed ocular disease. Increasing age induces structural alterations and functional impairments in retinal neurons and microvasculature linked to the activation of proinflammatory signaling pathways. Commona...

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Veröffentlicht in:	Molecular vision 2011, Vol.17, p.1261-1274
Hauptverfasser:	Van Kirk, Colleen A, VanGuilder, Heather D, Young, Megan, Farley, Julie A, Sonntag, William E, Freeman, Willard M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animals Blood Glucose - metabolism Hybridization, Genetic Inflammation - genetics Male Microcirculation - genetics Neurons - physiology Rats Rats, Inbred BN Rats, Inbred F344 Retina - metabolism Retinal Vessels - physiology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism
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