Bariatric surgery for type 2 diabetes: weighing the impact for obese patients

Obesity is a potent risk factor for the development and progression of type 2 diabetes, and weight loss is a key component of diabetes management. Bariatric surgery results in significant weight loss and remission of diabetes in most patients. After surgery, glycemic control is restored by a combina...

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Veröffentlicht in:	Cleveland Clinic journal of medicine 2010-07, Vol.77 (7), p.468-476
Hauptverfasser:	Kashyap, Sangeeta R, Gatmaitan, Patrick, Brethauer, Stacy, Schauer, Philip
Format:	Artikel
Sprache:	eng
Schlagworte:	Bariatric Surgery - statistics & numerical data Body Mass Index Caloric Restriction Diabetes Mellitus, Type 2 - physiopathology Diabetes Mellitus, Type 2 - surgery Disease Management Disease Progression Gastric Bypass - methods Gastric Bypass - statistics & numerical data Gastric Inhibitory Polypeptide - metabolism Glucagon-Like Peptide 1 - metabolism Humans Insulin - metabolism Insulin Resistance Insulin Secretion Risk Factors Weight Loss
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Beschreibung
Zusammenfassung:	Obesity is a potent risk factor for the development and progression of type 2 diabetes, and weight loss is a key component of diabetes management. Bariatric surgery results in significant weight loss and remission of diabetes in most patients. After surgery, glycemic control is restored by a combination of enforced caloric restriction, enhanced insulin sensitivity, and increased insulin secretion.
ISSN:	0891-1150 1939-2869
DOI:	10.3949/ccjm.77a.09135