Biocompatible and pH-Sensitive PLGA Encapsulated MnO Nanocrystals for Molecular and Cellular MRI

Inorganic manganese-based particles are becoming attractive for molecular and cellular imaging, due to their ability to provide bright contrast on MRI, as opposed to the dark contrast generated from iron-based particles. Using a single emulsion technique, we have successfully fabricated pH-sensitive...

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Veröffentlicht in:	ACS nano 2011-05, Vol.5 (5), p.3438-3446
Hauptverfasser:	Bennewitz, Margaret F, Lobo, Tricia L, Nkansah, Michael K, Ulas, Gözde, Brudvig, Gary W, Shapiro, Erik M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatible Materials - chemical synthesis Cell Line, Tumor Cell Tracking - methods Contrast Media - chemical synthesis Contrast Media - pharmacokinetics Glioblastoma - metabolism Glioblastoma - pathology Humans Hydrogen-Ion Concentration Lactic Acid - chemistry Manganese Compounds - pharmacokinetics Nanostructures - chemistry Oxides - pharmacokinetics Polyglycolic Acid - chemistry
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