Approach to the Girl with Early Onset of Pubic Hair
Premature adrenarche is often associated with insulin resistance, metabolic syndrome, and PCOS; evaluation and management during childhood and adolescence are described. Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by prematu...
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| Veröffentlicht in: | The journal of clinical endocrinology and metabolism 2011-06, Vol.96 (6), p.1610-1622 |
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| container_title | The journal of clinical endocrinology and metabolism |
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| creator | Oberfield, Sharon E Sopher, Aviva B Gerken, Adrienne T |
| description | Premature adrenarche is often associated with insulin resistance, metabolic syndrome, and PCOS; evaluation and management during childhood and adolescence are described.
Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by premature adrenarche. Adrenarche is the maturation of the adrenal zona reticularis in both boys and girls, resulting in the development of pubic hair, axillary hair, and adult apocrine body odor. Although originally thought to be a benign variant of normal development, premature adrenarche has been associated with insulin resistance and the later development of metabolic syndrome and polycystic ovary syndrome. Although further studies are needed to confirm these relationships, the case presented herein argues for periodic assessment of children at risk. Indeed, recognition of these associations may allow for early preventive measures. |
| doi_str_mv | 10.1210/jc.2011-0225 |
| format | Article |
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Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by premature adrenarche. Adrenarche is the maturation of the adrenal zona reticularis in both boys and girls, resulting in the development of pubic hair, axillary hair, and adult apocrine body odor. Although originally thought to be a benign variant of normal development, premature adrenarche has been associated with insulin resistance and the later development of metabolic syndrome and polycystic ovary syndrome. Although further studies are needed to confirm these relationships, the case presented herein argues for periodic assessment of children at risk. Indeed, recognition of these associations may allow for early preventive measures.</description><subject>Absorptiometry, Photon</subject><subject>Adolescent</subject><subject>Adrenarche</subject><subject>Biological and medical sciences</subject><subject>Body Composition</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Endocrinopathies</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hair - growth & development</subject><subject>Humans</subject><subject>Insulin Resistance</subject><subject>Medical sciences</subject><subject>Polycystic Ovary Syndrome - diagnosis</subject><subject>Polycystic Ovary Syndrome - etiology</subject><subject>Puberty, Precocious - complications</subject><subject>Puberty, Precocious - diagnosis</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Vertebrates: endocrinology</subject><issn>0021-972X</issn><issn>1945-7197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtr3DAUhUVJaKZJd10HbUI38fTqYUveFIYhj8JAumghOyFrrjMaPJYr2Qn597WZaZJCVndxP845fIR8YTBnnMG3rZtzYCwDzvMPZMZKmWeKleqIzAA4y0rF70_Ip5S2AEzKXHwkJ5wVwGUuZ0Qsui4G6za0D7TfIL3xsaFPvt_QKxubZ3rXJuxpqOnPofKO3lofz8hxbZuEnw_3lPy-vvq1vM1Wdzc_lotV5mSu-kwKxyUwLCvNa15IwddWIaIqHDjEohgXqJIVJcslr0DrnK-5FrrWtnJ1bcUp-b7P7YZqh2uHbR9tY7rodzY-m2C9-f_T-o15CI9GMACVwxjw9RAQw58BU292PjlsGttiGJLRhRZKa5jIyz3pYkgpYv3SwsBMms3WmUmzmTSP-PnbZS_wP68jcHEAbHK2qaNtnU-vnOQgFEyc2HPYroOLvsUuYkpmG4bYjm7fr_8LZhuUuQ</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Oberfield, Sharon E</creator><creator>Sopher, Aviva B</creator><creator>Gerken, Adrienne T</creator><general>Endocrine Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110601</creationdate><title>Approach to the Girl with Early Onset of Pubic Hair</title><author>Oberfield, Sharon E ; Sopher, Aviva B ; Gerken, Adrienne T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-43c2401e9b82f26432da7eee76c0cee66245791691542b08852d2838f8abcffa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Absorptiometry, Photon</topic><topic>Adolescent</topic><topic>Adrenarche</topic><topic>Biological and medical sciences</topic><topic>Body Composition</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Endocrinopathies</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hair - growth & development</topic><topic>Humans</topic><topic>Insulin Resistance</topic><topic>Medical sciences</topic><topic>Polycystic Ovary Syndrome - diagnosis</topic><topic>Polycystic Ovary Syndrome - etiology</topic><topic>Puberty, Precocious - complications</topic><topic>Puberty, Precocious - diagnosis</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oberfield, Sharon E</creatorcontrib><creatorcontrib>Sopher, Aviva B</creatorcontrib><creatorcontrib>Gerken, Adrienne T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The journal of clinical endocrinology and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oberfield, Sharon E</au><au>Sopher, Aviva B</au><au>Gerken, Adrienne T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Approach to the Girl with Early Onset of Pubic Hair</atitle><jtitle>The journal of clinical endocrinology and metabolism</jtitle><addtitle>J Clin Endocrinol Metab</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>96</volume><issue>6</issue><spage>1610</spage><epage>1622</epage><pages>1610-1622</pages><issn>0021-972X</issn><eissn>1945-7197</eissn><coden>JCEMAZ</coden><abstract>Premature adrenarche is often associated with insulin resistance, metabolic syndrome, and PCOS; evaluation and management during childhood and adolescence are described.
Premature pubarche, or the development of pubic hair before the age of 8 in girls or 9 in boys, is most commonly caused by premature adrenarche. Adrenarche is the maturation of the adrenal zona reticularis in both boys and girls, resulting in the development of pubic hair, axillary hair, and adult apocrine body odor. Although originally thought to be a benign variant of normal development, premature adrenarche has been associated with insulin resistance and the later development of metabolic syndrome and polycystic ovary syndrome. Although further studies are needed to confirm these relationships, the case presented herein argues for periodic assessment of children at risk. Indeed, recognition of these associations may allow for early preventive measures.</abstract><cop>Bethesda, MD</cop><pub>Endocrine Society</pub><pmid>21602454</pmid><doi>10.1210/jc.2011-0225</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The journal of clinical endocrinology and metabolism, 2011-06, Vol.96 (6), p.1610-1622 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Absorptiometry, Photon Adolescent Adrenarche Biological and medical sciences Body Composition Child Child, Preschool Endocrinopathies Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Hair - growth & development Humans Insulin Resistance Medical sciences Polycystic Ovary Syndrome - diagnosis Polycystic Ovary Syndrome - etiology Puberty, Precocious - complications Puberty, Precocious - diagnosis Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology |
| title | Approach to the Girl with Early Onset of Pubic Hair |
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