Feasibility of Repurposing the Polyanionic Microbicide, PPCM, for Prophylaxis against HIV Transmission during ART

HIV-serodiscordant couples wishing to conceive often seek assisted reproduction, during which spermatozoa from infected men are washed to minimize the risk of HIV transmission to partner and fetus. We sought to improve this method by adding a microbicide, PPCM, as an HIV prophylactic. HIV-1 (BaL) in...

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Veröffentlicht in:	ISRN obstetrics and gynecology 2011, Vol.2011 (2011), p.1-13
Hauptverfasser:	Anderson, Robert A., Brown, David, Jackson, Erin M., Feathergill, Kenneth A., Bremer, James W., Morack, Ralph, Rawlins, Richard G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-infective agents Antibiotics Clinical trials Disease transmission Dosage and administration Heparan sulfate Hepatitis HIV HIV infection Human immunodeficiency virus Human immunodeficiency virus 1 Management Prevention Reproductive technologies Reproductive technology Risk factors Sperm Viral infections
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