Pterin chemistry and its relationship to the molybdenum cofactor

Pterin chemistry and its relationship to the molybdenum cofactor

The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to per...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Coordination chemistry reviews 2011-05, Vol.255 (9), p.1016-1038
Hauptverfasser: Basu, Partha, Burgmayer, Sharon J.N.
Format: Artikel
Sprache:eng
Schlagworte:
Biosynthesis
Chemical synthesis
Molybdenum
Pterin
Redox reaction
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1038
container_issue 9
container_start_page 1016
container_title Coordination chemistry reviews
container_volume 255
creator Basu, Partha
Burgmayer, Sharon J.N.
description The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterins and current models of the molybdenum cofactor are discussed.
doi_str_mv 10.1016/j.ccr.2011.02.010
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3098623</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0010854511000683</els_id><sourcerecordid>1835551085</sourcerecordid><originalsourceid>FETCH-LOGICAL-c517t-b8e83ef490e474131b69c827d912caefa6bd2a2431d863b785e69bbdbcbd8cda3</originalsourceid><addsrcrecordid>eNp9kE1rHDEMhk1JaLZJfkAvZY65zMSy58NDISQsbRJYaA_t2fhD0_UyM97a3oX993XYNCSXnISkV6-kh5DPQCug0F5vKmNCxShARVlFgX4gCxAdL7mo6QlZ0FwqRVM3Z-RTjJuctn3PPpIzBi3tAPoFuf2ZMLi5MGucXEzhUKjZFi7FIuCokvNzXLttkXyR1lhMfjxoi_NuKowflEk-XJDTQY0RL5_jOfn9_duv5UO5-nH_uLxblaaBLpVaoOA41D3FuquBg257I1hne2BG4aBabZliNQcrWq470WDba2210VYYq_g5uTn6bnd6QmtwTkGNchvcpMJBeuXk287s1vKP30tOe9Eyng2ung2C_7vDmGR-2OA4qhn9LkoQvGkaoKLJUjhKTfAxBhxe1gCVT-TlRmby8om8pExmzHnmy-v7Xib-o86Cr0cBZkp7h0FG43A2aF1Ak6T17h37f80Ele8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1835551085</pqid></control><display><type>article</type><title>Pterin chemistry and its relationship to the molybdenum cofactor</title><source>Elsevier ScienceDirect Journals</source><creator>Basu, Partha ; Burgmayer, Sharon J.N.</creator><creatorcontrib>Basu, Partha ; Burgmayer, Sharon J.N.</creatorcontrib><description>The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterins and current models of the molybdenum cofactor are discussed.</description><identifier>ISSN: 0010-8545</identifier><identifier>EISSN: 1873-3840</identifier><identifier>DOI: 10.1016/j.ccr.2011.02.010</identifier><identifier>PMID: 21607119</identifier><language>eng</language><publisher>Switzerland: Elsevier B.V</publisher><subject>Biosynthesis ; Chemical synthesis ; Molybdenum ; Pterin ; Redox reaction</subject><ispartof>Coordination chemistry reviews, 2011-05, Vol.255 (9), p.1016-1038</ispartof><rights>2011 Elsevier B.V.</rights><rights>2011 Elsevier B.V. All rights reserved. 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-b8e83ef490e474131b69c827d912caefa6bd2a2431d863b785e69bbdbcbd8cda3</citedby><cites>FETCH-LOGICAL-c517t-b8e83ef490e474131b69c827d912caefa6bd2a2431d863b785e69bbdbcbd8cda3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ccr.2011.02.010$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21607119$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Basu, Partha</creatorcontrib><creatorcontrib>Burgmayer, Sharon J.N.</creatorcontrib><title>Pterin chemistry and its relationship to the molybdenum cofactor</title><title>Coordination chemistry reviews</title><addtitle>Coord Chem Rev</addtitle><description>The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterins and current models of the molybdenum cofactor are discussed.</description><subject>Biosynthesis</subject><subject>Chemical synthesis</subject><subject>Molybdenum</subject><subject>Pterin</subject><subject>Redox reaction</subject><issn>0010-8545</issn><issn>1873-3840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kE1rHDEMhk1JaLZJfkAvZY65zMSy58NDISQsbRJYaA_t2fhD0_UyM97a3oX993XYNCSXnISkV6-kh5DPQCug0F5vKmNCxShARVlFgX4gCxAdL7mo6QlZ0FwqRVM3Z-RTjJuctn3PPpIzBi3tAPoFuf2ZMLi5MGucXEzhUKjZFi7FIuCokvNzXLttkXyR1lhMfjxoi_NuKowflEk-XJDTQY0RL5_jOfn9_duv5UO5-nH_uLxblaaBLpVaoOA41D3FuquBg257I1hne2BG4aBabZliNQcrWq470WDba2210VYYq_g5uTn6bnd6QmtwTkGNchvcpMJBeuXk287s1vKP30tOe9Eyng2ung2C_7vDmGR-2OA4qhn9LkoQvGkaoKLJUjhKTfAxBhxe1gCVT-TlRmby8om8pExmzHnmy-v7Xib-o86Cr0cBZkp7h0FG43A2aF1Ak6T17h37f80Ele8</recordid><startdate>20110501</startdate><enddate>20110501</enddate><creator>Basu, Partha</creator><creator>Burgmayer, Sharon J.N.</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110501</creationdate><title>Pterin chemistry and its relationship to the molybdenum cofactor</title><author>Basu, Partha ; Burgmayer, Sharon J.N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-b8e83ef490e474131b69c827d912caefa6bd2a2431d863b785e69bbdbcbd8cda3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Biosynthesis</topic><topic>Chemical synthesis</topic><topic>Molybdenum</topic><topic>Pterin</topic><topic>Redox reaction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Basu, Partha</creatorcontrib><creatorcontrib>Burgmayer, Sharon J.N.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Coordination chemistry reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Basu, Partha</au><au>Burgmayer, Sharon J.N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pterin chemistry and its relationship to the molybdenum cofactor</atitle><jtitle>Coordination chemistry reviews</jtitle><addtitle>Coord Chem Rev</addtitle><date>2011-05-01</date><risdate>2011</risdate><volume>255</volume><issue>9</issue><spage>1016</spage><epage>1038</epage><pages>1016-1038</pages><issn>0010-8545</issn><eissn>1873-3840</eissn><abstract>The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterins and current models of the molybdenum cofactor are discussed.</abstract><cop>Switzerland</cop><pub>Elsevier B.V</pub><pmid>21607119</pmid><doi>10.1016/j.ccr.2011.02.010</doi><tpages>23</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0010-8545
ispartof Coordination chemistry reviews, 2011-05, Vol.255 (9), p.1016-1038
issn 0010-8545
1873-3840
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3098623
source Elsevier ScienceDirect Journals
subjects Biosynthesis
Chemical synthesis
Molybdenum
Pterin
Redox reaction
title Pterin chemistry and its relationship to the molybdenum cofactor
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T07%3A30%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pterin%20chemistry%20and%20its%20relationship%20to%20the%20molybdenum%20cofactor&rft.jtitle=Coordination%20chemistry%20reviews&rft.au=Basu,%20Partha&rft.date=2011-05-01&rft.volume=255&rft.issue=9&rft.spage=1016&rft.epage=1038&rft.pages=1016-1038&rft.issn=0010-8545&rft.eissn=1873-3840&rft_id=info:doi/10.1016/j.ccr.2011.02.010&rft_dat=%3Cproquest_pubme%3E1835551085%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1835551085&rft_id=info:pmid/21607119&rft_els_id=S0010854511000683&rfr_iscdi=true