Effect of diet-induced obesity and metabolic syndrome on skeletal muscles of Ossabaw miniature swine

Ossabaw swine fed excess kilocalorie diet develop metabolic syndrome (MS) characterized by obesity, hypertension, insulin resistance, and glucose intolerance with/without dyslipidemia. The purpose of this study was to test the hypothesis that MS would have a detrimental effect on skeletal muscle str...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2011-05, Vol.300 (5), p.E848-E857
Hauptverfasser:	Clark, Bradley A, Alloosh, Mouhamad, Wenzel, James W, Sturek, Michael, Kostrominova, Tatiana Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy, Cross-Sectional Animals Blotting, Western Cholesterol - blood Diet Gene expression Hogs Immunohistochemistry Lipid Metabolism - physiology Lipids Low density lipoprotein Male Metabolic syndrome Metabolic Syndrome - genetics Metabolic Syndrome - metabolism Metabolic Syndrome - pathology Muscle Fibers, Fast-Twitch - pathology Muscle Fibers, Fast-Twitch - physiology Muscle Fibers, Skeletal - pathology Muscle Fibers, Skeletal - physiology Muscle Fibers, Slow-Twitch - pathology Muscle Fibers, Slow-Twitch - physiology Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscle, Skeletal - pathology Musculoskeletal system Myosin Heavy Chains - metabolism Obesity Obesity - metabolism Reverse Transcriptase Polymerase Chain Reaction Swine Swine, Miniature Triglycerides - blood
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