Enzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex

Malaria continues to be a major cause of children's morbidity and mortality worldwide, causing nearly one million deaths annually. The human malaria parasite, Plasmodium falciparum, synthesizes fatty acids employing the Type II fatty acid biosynthesis system (FAS II), unlike humans that rely on...

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Veröffentlicht in:	Enzyme Research 2011, Vol.2011 (2011), p.668-678
Hauptverfasser:	Medeiros, Patrícia Soares de Maria de, Ducati, Rodrigo Gay, Basso, Luiz Augusto, Santos, Diógenes Santiago, da Silva, Luiz Hildebrando Pereira
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell membranes Malaria Physiological aspects Plasmodium falciparum
Online-Zugang:	Volltext
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