Vitamin D3 correlates inversely with systemic dendritic cell numbers and bone erosion in chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis

Summary Vitamin D3 (VD3) is a steroid hormone that regulates bone health and numerous aspects of immune function and may play a role in respiratory health. We hypothesized that T helper type 2 (Th2) disorders, chronic rhinosinusitis with nasal polyps (CRSwNP) and allergic fungal rhinosinusitis (AFRS...

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Veröffentlicht in:	Clinical and experimental immunology 2011-06, Vol.164 (3), p.312-320
Hauptverfasser:	Mulligan, J. K., Bleier, B. S., O'Connell, B., Mulligan, R. M., Wagner, C., Schlosser, R. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	allergic fungal rhinosinusitis Analytical, structural and metabolic biochemistry Biological and medical sciences Blood Circulation - immunology bone erosion Bone Remodeling - immunology Cell Count Cells, Cultured Cerebrospinal fluid Cholecalciferol - blood Chronic Disease chronic rhinosinusitis Dendritic cells Dendritic Cells - immunology Dendritic Cells - metabolism Dendritic Cells - pathology Drug therapy Enzyme-linked immunosorbent assay Flow cytometry Fundamental and applied biological sciences. Psychology Fungi - immunology Granulocyte-macrophage colony-stimulating factor Helper cells Humans Immune response Immune system Lymphocytes T Macrophages Macrophages - immunology Macrophages - metabolism Macrophages - pathology Medical research Medical sciences Nasal Polyps Non tumoral diseases Otorhinolaryngology. Stomatology Polyps Prostaglandin E2 Rhinitis - blood Rhinitis - immunology Rhinitis - physiopathology Rhinitis, Allergic, Perennial - blood Rhinitis, Allergic, Perennial - immunology Rhinitis, Allergic, Perennial - physiopathology rhinosinusitis Sinusitis - blood Sinusitis - immunology Sinusitis - physiopathology Steroid hormones Surgery Th1-Th2 Balance Translational Studies Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology vitamin D Vitamin D3
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