Rapid intrapartum or postpartum HIV testing at a midwife obstetric unit and a district hospital in South Africa
Abstract Objective To compare the prepartum and postpartum feasibility and acceptance of voluntary counseling and rapid testing (VCT) among women with unknown HIV status in South Africa. Methods Eligible women were randomized according to the calendar week of presentation to receive VCT either while...
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| Veröffentlicht in: | International journal of gynecology and obstetrics 2011-04, Vol.113 (1), p.44-49 |
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| container_title | International journal of gynecology and obstetrics |
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| creator | Theron, Gerhard B Shapiro, David E Van Dyke, Russell Cababasay, Mae P Louw, Jeanne Watts, D. Heather Smith, Elizabeth Bulterys, Marc Maupin, Robert |
| description | Abstract Objective To compare the prepartum and postpartum feasibility and acceptance of voluntary counseling and rapid testing (VCT) among women with unknown HIV status in South Africa. Methods Eligible women were randomized according to the calendar week of presentation to receive VCT either while in labor or after delivery. Results Of 7238 women approached, 542 (7.5%) were eligible, 343 (63%) were enrolled, and 45 (13%) were found to be HIV infected. The proportions of eligible women who accepted VCT were 66.8% (161 of 241) in the intrapartum arm and 60.5% (182 of 301) in the postpartum arm, and the difference of 6.3% (95% CI, − 1.8% to 14.5%) was not significant. The median times (44 and 45 minutes) required to conduct VCT were also similar in the 2 arms. In the intrapartum arm, all women in true labor received their test results before delivery and all those found to be HIV positive accepted prophylaxis with nevirapine before delivery. Conclusions Rapid testing in labor wards for women with an unknown HIV status is feasible and well accepted, and allows for a more timely antiretroviral prophylaxis than postpartum testing. |
| doi_str_mv | 10.1016/j.ijgo.2010.10.011 |
| format | Article |
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Heather ; Smith, Elizabeth ; Bulterys, Marc ; Maupin, Robert</creator><creatorcontrib>Theron, Gerhard B ; Shapiro, David E ; Van Dyke, Russell ; Cababasay, Mae P ; Louw, Jeanne ; Watts, D. Heather ; Smith, Elizabeth ; Bulterys, Marc ; Maupin, Robert</creatorcontrib><description>Abstract Objective To compare the prepartum and postpartum feasibility and acceptance of voluntary counseling and rapid testing (VCT) among women with unknown HIV status in South Africa. Methods Eligible women were randomized according to the calendar week of presentation to receive VCT either while in labor or after delivery. Results Of 7238 women approached, 542 (7.5%) were eligible, 343 (63%) were enrolled, and 45 (13%) were found to be HIV infected. The proportions of eligible women who accepted VCT were 66.8% (161 of 241) in the intrapartum arm and 60.5% (182 of 301) in the postpartum arm, and the difference of 6.3% (95% CI, − 1.8% to 14.5%) was not significant. The median times (44 and 45 minutes) required to conduct VCT were also similar in the 2 arms. In the intrapartum arm, all women in true labor received their test results before delivery and all those found to be HIV positive accepted prophylaxis with nevirapine before delivery. Conclusions Rapid testing in labor wards for women with an unknown HIV status is feasible and well accepted, and allows for a more timely antiretroviral prophylaxis than postpartum testing.</description><identifier>ISSN: 0020-7292</identifier><identifier>EISSN: 1879-3479</identifier><identifier>DOI: 10.1016/j.ijgo.2010.10.011</identifier><identifier>PMID: 21251654</identifier><identifier>CODEN: IJGOAL</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adolescent ; Adult ; Anti-HIV Agents - therapeutic use ; Biological and medical sciences ; Cluster Analysis ; Delivery. Postpartum. Lactation ; Feasibility Studies ; Female ; Gynecology. Andrology. Obstetrics ; HIV Infections - complications ; HIV Infections - diagnosis ; HIV Infections - drug therapy ; HIV Seropositivity ; Hospitals, District ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Infectious diseases ; Labor ; Mass Screening - methods ; Medical sciences ; Midwifery ; Nevirapine - therapeutic use ; Obstetrics and Gynecology ; Patient Acceptance of Health Care ; Postpartum Period ; Pregnancy ; Pregnancy Complications, Infectious - diagnosis ; Pregnancy Complications, Infectious - drug therapy ; Prospective Studies ; Rapid testing ; South Africa ; Time Factors ; Unknown HIV status ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Young Adult</subject><ispartof>International journal of gynecology and obstetrics, 2011-04, Vol.113 (1), p.44-49</ispartof><rights>International Federation of Gynecology and Obstetrics</rights><rights>2010 International Federation of Gynecology and Obstetrics</rights><rights>2011 International Federation of Gynecology and Obstetrics</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 International Federation of Gynecology and Obstetrics. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5864-2a2d0f581bb38b4fe22b9590e3ff0e3e568345dcc756e3918dfca2d5690977103</citedby><cites>FETCH-LOGICAL-c5864-2a2d0f581bb38b4fe22b9590e3ff0e3e568345dcc756e3918dfca2d5690977103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1016%2Fj.ijgo.2010.10.011$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1016%2Fj.ijgo.2010.10.011$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24037785$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21251654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Theron, Gerhard B</creatorcontrib><creatorcontrib>Shapiro, David E</creatorcontrib><creatorcontrib>Van Dyke, Russell</creatorcontrib><creatorcontrib>Cababasay, Mae P</creatorcontrib><creatorcontrib>Louw, Jeanne</creatorcontrib><creatorcontrib>Watts, D. Heather</creatorcontrib><creatorcontrib>Smith, Elizabeth</creatorcontrib><creatorcontrib>Bulterys, Marc</creatorcontrib><creatorcontrib>Maupin, Robert</creatorcontrib><title>Rapid intrapartum or postpartum HIV testing at a midwife obstetric unit and a district hospital in South Africa</title><title>International journal of gynecology and obstetrics</title><addtitle>Int J Gynaecol Obstet</addtitle><description>Abstract Objective To compare the prepartum and postpartum feasibility and acceptance of voluntary counseling and rapid testing (VCT) among women with unknown HIV status in South Africa. Methods Eligible women were randomized according to the calendar week of presentation to receive VCT either while in labor or after delivery. Results Of 7238 women approached, 542 (7.5%) were eligible, 343 (63%) were enrolled, and 45 (13%) were found to be HIV infected. The proportions of eligible women who accepted VCT were 66.8% (161 of 241) in the intrapartum arm and 60.5% (182 of 301) in the postpartum arm, and the difference of 6.3% (95% CI, − 1.8% to 14.5%) was not significant. The median times (44 and 45 minutes) required to conduct VCT were also similar in the 2 arms. In the intrapartum arm, all women in true labor received their test results before delivery and all those found to be HIV positive accepted prophylaxis with nevirapine before delivery. Conclusions Rapid testing in labor wards for women with an unknown HIV status is feasible and well accepted, and allows for a more timely antiretroviral prophylaxis than postpartum testing.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cluster Analysis</subject><subject>Delivery. Postpartum. Lactation</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>HIV Infections - complications</subject><subject>HIV Infections - diagnosis</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Seropositivity</subject><subject>Hospitals, District</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Infectious diseases</subject><subject>Labor</subject><subject>Mass Screening - methods</subject><subject>Medical sciences</subject><subject>Midwifery</subject><subject>Nevirapine - therapeutic use</subject><subject>Obstetrics and Gynecology</subject><subject>Patient Acceptance of Health Care</subject><subject>Postpartum Period</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - diagnosis</subject><subject>Pregnancy Complications, Infectious - drug therapy</subject><subject>Prospective Studies</subject><subject>Rapid testing</subject><subject>South Africa</subject><subject>Time Factors</subject><subject>Unknown HIV status</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Young Adult</subject><issn>0020-7292</issn><issn>1879-3479</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUstu1DAUjRCIDoUfYIG8Qawy-BHHjoQqVRW0gypVosDWcpybGYdMnNpOq_n7Op2hPBaIjS3f87i2z82y1wQvCSbl-25pu7VbUvxQWGJCnmQLIkWVs0JUT7MFxhTnglb0KHsRQocxJoKQ59kRJZSTkheLzH3Ro22QHaLXo_Zx2iLn0ehCPJwuVt9RhBDtsEY6Io22trmzLSBXhwjRW4OmwSZgaBLY2DCXItq4MNqo--SMrt0UN-i0TYB-mT1rdR_g1WE_zr59-vj17CK_vDpfnZ1e5obLssippg1uuSR1zWRdtEBpXfEKA2vbtAAvJSt4Y4zgJbCKyKY1ScLLCldCEMyOs5O97zjVW2gMzA_s1ejtVvudctqqP5HBbtTa3SqGpSgxSwbvDgbe3UzpA9TWBgN9rwdwU1CSSyp5QURi0j3TeBeCh_axC8FqDkp1ag5KzUHNtRRUEr35_X6Pkp_JJMLbA0EHo_vW68HY8ItXYCaE5IlX7nl3tofdf7RWq8_nV8Xc4MNeCCmGWwteBWNhMNBYDyaqxtl_P-DkL7np7ZAS7n_ADkLnJj-kgBVRgSqsrudZnEeRpCnkQjJ2D4bM2Os</recordid><startdate>201104</startdate><enddate>201104</enddate><creator>Theron, Gerhard B</creator><creator>Shapiro, David E</creator><creator>Van Dyke, Russell</creator><creator>Cababasay, Mae P</creator><creator>Louw, Jeanne</creator><creator>Watts, D. Heather</creator><creator>Smith, Elizabeth</creator><creator>Bulterys, Marc</creator><creator>Maupin, Robert</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201104</creationdate><title>Rapid intrapartum or postpartum HIV testing at a midwife obstetric unit and a district hospital in South Africa</title><author>Theron, Gerhard B ; Shapiro, David E ; Van Dyke, Russell ; Cababasay, Mae P ; Louw, Jeanne ; Watts, D. Heather ; Smith, Elizabeth ; Bulterys, Marc ; Maupin, Robert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5864-2a2d0f581bb38b4fe22b9590e3ff0e3e568345dcc756e3918dfca2d5690977103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cluster Analysis</topic><topic>Delivery. Postpartum. Lactation</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>HIV Infections - complications</topic><topic>HIV Infections - diagnosis</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Seropositivity</topic><topic>Hospitals, District</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infectious diseases</topic><topic>Labor</topic><topic>Mass Screening - methods</topic><topic>Medical sciences</topic><topic>Midwifery</topic><topic>Nevirapine - therapeutic use</topic><topic>Obstetrics and Gynecology</topic><topic>Patient Acceptance of Health Care</topic><topic>Postpartum Period</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - diagnosis</topic><topic>Pregnancy Complications, Infectious - drug therapy</topic><topic>Prospective Studies</topic><topic>Rapid testing</topic><topic>South Africa</topic><topic>Time Factors</topic><topic>Unknown HIV status</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Theron, Gerhard B</creatorcontrib><creatorcontrib>Shapiro, David E</creatorcontrib><creatorcontrib>Van Dyke, Russell</creatorcontrib><creatorcontrib>Cababasay, Mae P</creatorcontrib><creatorcontrib>Louw, Jeanne</creatorcontrib><creatorcontrib>Watts, D. Heather</creatorcontrib><creatorcontrib>Smith, Elizabeth</creatorcontrib><creatorcontrib>Bulterys, Marc</creatorcontrib><creatorcontrib>Maupin, Robert</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of gynecology and obstetrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Theron, Gerhard B</au><au>Shapiro, David E</au><au>Van Dyke, Russell</au><au>Cababasay, Mae P</au><au>Louw, Jeanne</au><au>Watts, D. Heather</au><au>Smith, Elizabeth</au><au>Bulterys, Marc</au><au>Maupin, Robert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rapid intrapartum or postpartum HIV testing at a midwife obstetric unit and a district hospital in South Africa</atitle><jtitle>International journal of gynecology and obstetrics</jtitle><addtitle>Int J Gynaecol Obstet</addtitle><date>2011-04</date><risdate>2011</risdate><volume>113</volume><issue>1</issue><spage>44</spage><epage>49</epage><pages>44-49</pages><issn>0020-7292</issn><eissn>1879-3479</eissn><coden>IJGOAL</coden><abstract>Abstract Objective To compare the prepartum and postpartum feasibility and acceptance of voluntary counseling and rapid testing (VCT) among women with unknown HIV status in South Africa. Methods Eligible women were randomized according to the calendar week of presentation to receive VCT either while in labor or after delivery. Results Of 7238 women approached, 542 (7.5%) were eligible, 343 (63%) were enrolled, and 45 (13%) were found to be HIV infected. The proportions of eligible women who accepted VCT were 66.8% (161 of 241) in the intrapartum arm and 60.5% (182 of 301) in the postpartum arm, and the difference of 6.3% (95% CI, − 1.8% to 14.5%) was not significant. The median times (44 and 45 minutes) required to conduct VCT were also similar in the 2 arms. In the intrapartum arm, all women in true labor received their test results before delivery and all those found to be HIV positive accepted prophylaxis with nevirapine before delivery. Conclusions Rapid testing in labor wards for women with an unknown HIV status is feasible and well accepted, and allows for a more timely antiretroviral prophylaxis than postpartum testing.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>21251654</pmid><doi>10.1016/j.ijgo.2010.10.011</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Anti-HIV Agents - therapeutic use Biological and medical sciences Cluster Analysis Delivery. Postpartum. Lactation Feasibility Studies Female Gynecology. Andrology. Obstetrics HIV Infections - complications HIV Infections - diagnosis HIV Infections - drug therapy HIV Seropositivity Hospitals, District Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Labor Mass Screening - methods Medical sciences Midwifery Nevirapine - therapeutic use Obstetrics and Gynecology Patient Acceptance of Health Care Postpartum Period Pregnancy Pregnancy Complications, Infectious - diagnosis Pregnancy Complications, Infectious - drug therapy Prospective Studies Rapid testing South Africa Time Factors Unknown HIV status Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Young Adult |
| title | Rapid intrapartum or postpartum HIV testing at a midwife obstetric unit and a district hospital in South Africa |
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