Fibulin-5: two for the price of one maintaining pelvic support

Pelvic organ prolapse (POP) is a disabling disorder in women characterized by a loss of pelvic floor support leading to the herniation of the uterus into or through the vagina. POP is a complex problem that likely involves multiple mechanisms, and available therapies are limited. In this issue of th...

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Veröffentlicht in:	The Journal of clinical investigation 2011-05, Vol.121 (5), p.1688-1691
1. Verfasser:	Northington, Gina M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical research Disease Models, Animal Elastic Tissue - metabolism Elastin - chemistry Extracellular Matrix Proteins - metabolism Female Glycoproteins Humans Matrix Metalloproteinase 9 - metabolism Mice Mice, Transgenic Pelvic Floor - pathology Pelvic Organ Prolapse Pelvis Physiological aspects Prolapse Protein Structure, Tertiary Risk factors Tropoelastin - chemistry Vagina - pathology
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