Identification of an Interaction between the TPα and TPβ Isoforms of the Human Thromboxane A2 Receptor with Protein Kinase C-related Kinase (PRK) 1: IMPLICATIONS FOR PROSTATE CANCER

In humans, thromboxane (TX) A2 signals through the TPα and TPβ isoforms of the TXA2 receptor or TP. Here, the RhoA effector protein kinase C-related kinase (PRK) 1 was identified as an interactant of both TPα and ΤPβ involving common and unique sequences within their respective C-terminal (C)-tail d...

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Veröffentlicht in:	The Journal of biological chemistry 2011-04, Vol.286 (17), p.15440-15457
Hauptverfasser:	Turner, Elizebeth C., Kavanagh, David J., Mulvaney, Eamon P., McLean, Caitriona, Wikström, Katarina, Reid, Helen M., Kinsella, B. Therese
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Helix 8 Cancer Histone Modification Molecular Bases of Disease Prostaglandins Prostate Protein Kinase C-related Kinase 1 Protein Kinases Receptors Rho Thromboxane Receptor
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