The heterodimeric subunit SRP9/14 of the signal recognition particle functions as permuted single polypeptide chain

The targeting of nascent polypeptide chains to the endoplasmic reticulum is mediated by a cytoplasmic ribonucleoprotein, the signal recognition particle (SRP). The 9 kD (SRP9) and the 14 kD (SRP14) subunits of SRP are required to confer elongation arrest activity to the particle. SRP9 and SRP14 form...

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Veröffentlicht in:	Nucleic acids research 1994-06, Vol.22 (11), p.2028-2035
Hauptverfasser:	Bovia, Fabrice, Bui, Nazarena, Strub, Katharina
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences Cloning, Molecular Endoplasmic Reticulum - metabolism Escherichia coli - metabolism Fundamental and applied biological sciences. Psychology Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleic Acid Heteroduplexes Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - metabolism RNA - metabolism Signal Recognition Particle - chemistry Signal Recognition Particle - genetics Translation. Translation factors. Protein processing
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