X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein―Barr virus in co-infected primary effusion lymphoma

Cells of primary effusion lymphoma (PEL), a B-cell non-Hodgkin's lymphoma, are latently infected by Kaposi's sarcoma-associated herpesvirus (KSHV), with about 80 % of PEL also co-infected with Epstein-Barr virus (EBV). Both viruses can be reactivated into their lytic replication cycle in P...

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Veröffentlicht in:	Journal of general virology 2011-02, Vol.92 (Pt 2), p.421-431
Hauptverfasser:	LAI, Imogen Yi-Chun, FARRELL, Paul J, KELLAM, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Cell Line, Tumor DNA-Binding Proteins - pharmacology Epstein-Barr virus Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Viral - physiology Herpesvirus 4, Human - genetics Herpesvirus 4, Human - metabolism Herpesvirus 8, Human - genetics Herpesvirus 8, Human - metabolism Human herpesvirus 8 Humans Kaposi's sarcoma-associated herpesvirus Lymphoma, Primary Effusion - metabolism Lymphoma, Primary Effusion - virology Medical sciences Microbiology Miscellaneous Regulatory Factor X Transcription Factors Trans-Activators Transcription Factors - pharmacology Tumors Viral Proteins - genetics Viral Proteins - metabolism Virology Viruses X-Box Binding Protein 1
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