The effect of ethinylestradiol‐containing contraceptives on the serum concentration of olanzapine and N‐desmethyl olanzapine

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Olanzapine is metabolized via CYP1A2, which is inhibited by ethinylestradiol‐containing contraceptives (ECC). WHAT THIS PAPER ADDS • A lower serum concentration of the metabolite N‐desmethyl olanzapine during co‐administration of ECC confirms a CYP1A2‐inhib...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of clinical pharmacology 2011-04, Vol.71 (4), p.611-615
Hauptverfasser:	Haslemo, Tore, Refsum, Helge, Molden, Espen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analysis of Variance Antipsychotic Agents - blood Antipsychotic Agents - pharmacology Benzodiazepines - blood Benzodiazepines - pharmacology Biological and medical sciences Contraceptive Agents - blood Contraceptive Agents - pharmacology contraceptives CYP1A2 Cytochrome P-450 CYP1A2 - metabolism drug interaction Drug Interactions Ethinyl Estradiol - blood Ethinyl Estradiol - pharmacology Female Humans Medical sciences N‐desmethyl olanzapine olanzapine Pharmacology. Drug treatments Pirenzepine - analogs & derivatives Pirenzepine - blood Pirenzepine - pharmacology Short Reports Surveys and Questionnaires Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!