Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase

Quinolinate phosphoribosyltransferase (QPRTase) is a key NAD‐biosynthetic enzyme which catalyzes the transfer of quinolinic acid to 5‐phosphoribosyl‐1‐pyrophosphate, yielding nicotinic acid mononucleotide. Homo sapiens QPRTase (Hs‐QPRTase) appeared as a hexamer during purification and the protein wa...

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Veröffentlicht in:	Acta crystallographica. Section F, Structural biology and crystallization communications Structural biology and crystallization communications, 2011-01, Vol.67 (1), p.38-40
Hauptverfasser:	Kang, Gil Bu, Kim, Mun-Kyoung, Youn, Hyung-Seop, An, Jun Yop, Lee, Jung-Gyu, Park, Kyoung Ryoung, Lee, Sung Hang, Kim, Yongseong, Fukuoka, Shin-Ichi, Eom, Soo Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Crystallization Crystallization Communications Crystallography Crystallography, X-Ray Human Humans Molecular Sequence Data NAD - biosynthesis NadC Pentosyltransferases - chemistry Pentosyltransferases - metabolism Protein Structure, Quaternary quinolinate phosphoribosyltransferase X-rays
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