Molecular Characteristics of Mantle Cell Lymphoma Presenting With Clonal Plasma Cell Component

The normal counterparts of mantle cell lymphoma (MCL) are naive, quiescent B cells that have not been processed through the germinal center (GC). For this reason, although lymphomas arising from GC or post-GC B cells often exhibit plasmacytic differentiation, MCL rarely presents with plasmacytic fea...

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Veröffentlicht in:	The American journal of surgical pathology 2011-02, Vol.35 (2), p.177-189
Hauptverfasser:	VISCO, Carlo, HOELLER, Sylvia, GRADOWSKI, Joel F, SERRANO, Sergio, WANG, Huan-You, QINGQUAN LIU, DAVE, Sandeep, OLSEN, Brian, GASCOYNE, Randy D, CAMPO, Elias, SWERDLOW, Steven H, CHAN, Wing C, MALIK, Jeffrey T, TZANKOV, Alexander, YOUNG, Ken H, XU-MONETTE, Zijun Y, WIGGINS, Michele L, LIU, Jessica, SANGER, Warren G, ZHONGFENG LIU, JULIE CHANG, RANHEIM, Erik A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - metabolism Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 14 Clone Cells DNA, Neoplasm - analysis Female Hematologic and hematopoietic diseases Humans Immunoenzyme Techniques Immunoglobulin Heavy Chains - genetics Immunophenotyping In Situ Hybridization, Fluorescence Investigative techniques, diagnostic techniques (general aspects) Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoid Tissue - metabolism Lymphoid Tissue - pathology Lymphoma, Mantle-Cell - genetics Lymphoma, Mantle-Cell - metabolism Lymphoma, Mantle-Cell - pathology Male Medical sciences Microdissection Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Plasma Cells - metabolism Plasma Cells - pathology Polymorphism, Restriction Fragment Length Translocation, Genetic - genetics
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