CpG-island methylation study of liver fluke-related cholangiocarcinoma

Background: Genetic changes have been widely reported in association with cholangiocarcinoma (CCA), while epigenetic changes are poorly characterised. We aimed to further evaluate CpG-island hypermethylation in CCA at candidate loci, which may have potential as diagnostic or prognostic biomarkers. M...

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Veröffentlicht in:	British journal of cancer 2011-04, Vol.104 (8), p.1313-1318
Hauptverfasser:	Sriraksa, R, Zeller, C, El-Bahrawy, M A, Dai, W, Daduang, J, Jearanaikoon, P, Chau-in, S, Brown, R, Limpaiboon, T
Format:	Artikel
Sprache:	eng
Schlagworte:	692/420/2489/2487/2486 692/53 692/699/67/1504/1329/1326 Aged Animals Apoptosis Bile Duct Neoplasms - etiology Bile Duct Neoplasms - genetics Bile Ducts, Intrahepatic - pathology Biomarkers Biomedical and Life Sciences Biomedicine Bisulfite Cancer Research Case-Control Studies Cell cycle Cholangiocarcinoma Cholangiocarcinoma - etiology Cholangiocarcinoma - genetics CpG Islands - genetics DNA Methylation DNA repair Drug Resistance Epidemiology Epigenetics Epigenomics Fasciola hepatica - physiology Fascioliasis - complications Female Humans Infections Liver Male Medical prognosis Medical research Middle Aged Molecular Diagnostics Molecular Medicine Oncology Protein expression R&D Research & development Surgery Trematoda
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