A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis

Glucose-regulated protein 78 (GRP78)/BiP is a multifunctional protein which plays a major role in endoplasmic reticulum (ER) protein processing, protein quality control, maintaining ER homeostasis, and controlling cell signaling and viability. Previously, using a transgene-induced mammary tumor mode...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2011-04, Vol.71 (8), p.2848-2857
Hauptverfasser:	DEZHENG DONG, STAPLETON, Christopher, BRUHN, Kevin W, CRAFT, Noah, GROSHEN, Susan, HOFMAN, Florence M, LEE, Amy S, BIQUAN LUO, SHIGANG XIONG, WEI YE, YI ZHANG, JHAVERI, Niyati, GENYUAN ZHU, RISHENG YE, ZHI LIU
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Apoptosis - physiology Biological and medical sciences Cell Growth Processes - physiology Cell Movement - physiology Endothelial Cells - cytology Endothelial Cells - physiology Female Heat-Shock Proteins - genetics Heterozygote Humans Mammary Neoplasms, Experimental - blood supply Mammary Neoplasms, Experimental - genetics Mammary Neoplasms, Experimental - pathology Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Neoplasm Metastasis Neovascularization, Pathologic - genetics Pharmacology. Drug treatments Tumor Microenvironment Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!