Sequence-independent Control of Peptide Conformation in Liposomal Vaccines for Targeting Protein Misfolding Diseases

Synthetic peptide immunogens that mimic the conformation of a target epitope of pathological relevance offer the possibility to precisely control the immune response specificity. Here, we performed conformational analyses using a panel of peptides in order to investigate the key parameters controlli...

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Veröffentlicht in:The Journal of biological chemistry 2011-04, Vol.286 (16), p.13966-13976
Hauptverfasser: Hickman, David T., López-Deber, María Pilar, Ndao, Dorin Mlaki, Silva, Alberto B., Nand, Deepak, Pihlgren, Maria, Giriens, Valérie, Madani, Rime, St-Pierre, Annie, Karastaneva, Hristina, Nagel-Steger, Luitgard, Willbold, Dieter, Riesner, Detlev, Nicolau, Claude, Baldus, Marc, Pfeifer, Andrea, Muhs, Andreas
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Sprache:eng
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