TGF-β and Restenosis Revisited: A Smad Link

Despite novel surgical therapies for the treatment of atherosclerosis, restenosis continues to be a significant impediment to the long-term success of vascular interventions. Transforming growth factor-beta (TGF-β), a family of cytokines found to be up-regulated at sites of arterial injury, has long...

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Veröffentlicht in:	The Journal of surgical research 2011-05, Vol.167 (2), p.287-297
Hauptverfasser:	Suwanabol, Pasithorn A., M.D, Kent, K. Craig, M.D, Liu, Bo, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	angioplasty Animals Biological and medical sciences Coronary Restenosis - physiopathology Disease Models, Animal Diseases of the cardiovascular system General aspects Humans intimal hyperplasia Medical sciences Mice Mice, Knockout Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) restenosis Signal Transduction - physiology Smad Smad Proteins - physiology Surgery Transforming Growth Factor beta - physiology transforming growth factor-beta (TGF-β) Tunica Intima - pathology Tunica Intima - physiopathology
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