Structural architecture of Galdieria sulphuraria DCN1L

NEDD8ylation is a major regulatory event for cullin-RING E3 ubiquitin ligases (CRL). NEDD8ylation activates the ubiquitylation activity of CRLs, which serves to regulate a wide variety of cellular processes by selecting specific targets for destruction in the proteasome. NEDD8 E3 ligases catalyze li...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2011-04, Vol.79 (4), p.1329-1336
Hauptverfasser:	Sethe Burgie, E., Bingman, Craig A., Makino, Shin-ichi, Wesenberg, Gary E., Pan, Xiaokang, Fox, Brian G., Phillips Jr, George N.
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Amino Acid Sequence AMINO ACIDS BASIC BIOLOGICAL SCIENCES CATALYSIS CONFORMATIONAL CHANGES Cullin-RING E3 ubiquitin ligase DCN1 ENZYMES FUNCTIONAL MODELS Galdieria sulphuraria LIGASES Models, Molecular Molecular Sequence Data Nedd8 Nedd8 E3 ligase neddylation protein regulation PROTEINS Rhodophyta - enzymology SACCHAROMYCES CEREVISIAE Sequence Alignment SUBSTRATES TARGETS Ubiquitin-Protein Ligases - chemistry Ubiquitin-Protein Ligases - metabolism
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