Properties and functions of the nucleocapsid protein in virus assembly

HIV-1 nucleocapsid protein (NC) is a small basic protein generated by the cleavage of the Gag structural polyprotein precusor by the viral protease during virus assembly in the infected cell. HIV-1 NC possesses two copies of a highly conserved CCHC zinc finger (ZnF), flanked by basic residues. HIV-1...

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Veröffentlicht in:	RNA biology 2010-11, Vol.7 (6), p.744-753
Hauptverfasser:	Muriaux, Delphine, Darlix, Jean-Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding binding proteins Biology Bioscience Calcium Cancer Cell Cycle dimerization DNA Gene Products, gag - chemistry Gene Products, gag - metabolism genomics Human immunodeficiency virus 1 Humans hydrophobicity Landes nucleic acid annealing nucleocapsid proteins Nucleocapsid Proteins - metabolism Organogenesis plasma membrane polyproteins Protein Binding Protein Structure, Tertiary proteinases Proteins Retroviridae - metabolism Review RNA RNA replication RNA, Viral - metabolism RNA-directed DNA polymerase Structure-Activity Relationship virion virus assembly Virus Assembly - physiology zinc finger motif
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