Minimal Model of Plasma Membrane Heterogeneity Requires Coupling Cortical Actin to Criticality

We present a minimal model of plasma membrane heterogeneity that combines criticality with connectivity to cortical cytoskeleton. The development of this model was motivated by recent observations of micron-sized critical fluctuations in plasma membrane vesicles that are detached from their cortical...

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Veröffentlicht in:	Biophysical journal 2011-04, Vol.100 (7), p.1668-1677
Hauptverfasser:	Machta, Benjamin B., Papanikolaou, Stefanos, Sethna, James P., Veatch, Sarah L.
Format:	Artikel
Sprache:	eng
Schlagworte:	actin Actins - chemistry Actins - metabolism Binding sites Cell Membrane - chemistry Cytoskeleton Cytoskeleton - metabolism Diffusion Membrane Membranes microfilaments Models, Biological Plasma plasma membrane Proteins Temperature Time Factors
Online-Zugang:	Volltext
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