USF binds to the APBα sequence in the promoter of the amyloid β-protein precursor gene

The APBα domain in the amyloid β-protein precursor (APP) promoter contains a nuclear factor binding domain with the core recognition sequence TCAGCTGAC. Proteins in nuclear extracts from brain and numerous cell lines bind to this domain and it contributes –10–30% to the basal APPα promoter activity....

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Veröffentlicht in:	Nucleic acids research 1995-07, Vol.23 (14), p.2734-2741
Hauptverfasser:	Vostrov, Alexander A., Quitschke, Wolfgang W., Vidal, Frédérique, Schwarzman, Alexander L., Goldaber, Dmitry
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenovirus Alternative Splicing Amyloid beta-Protein Precursor - genetics Animals Base Sequence Binding Sites - genetics Brain - metabolism Cattle DNA, Complementary - genetics DNA-Binding Proteins - genetics HeLa Cells Humans In Vitro Techniques Mice Molecular Sequence Data Promoter Regions, Genetic Protein Binding Protein Biosynthesis Rats Transcription Factors - metabolism Upstream Stimulatory Factors
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