Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation

Phosphoinositide 3-kinase (PI3K) defines a family of lipid kinases that direct a wide range of cellular processes and cell fate decisions. Since its discovery, and that of its enzymatic antagonist PTEN, much of the focus on PI3K has been on its oncogenic potential. In recent years, studies on PI3K s...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in immunology 2011-04, Vol.23 (2), p.178-183
Hauptverfasser:	Baracho, GV, Miletic, AV, Omori, SA, Cato, MH, Rickert, RC
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals B-Lymphocytes - cytology B-Lymphocytes - immunology B-Lymphocytes - metabolism Cell Differentiation Homeostasis Humans Phosphatidylinositol 3-Kinases - immunology Phosphatidylinositol 3-Kinases - metabolism Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!