Multiplexed Methylation Profiles of Tumor Suppressor Genes in Bladder Cancer

Changes in DNA methylation of tumor suppressors can occur early in carcinogenesis and are potentially important early indicators of cancer. The objective of this study was to assess the methylation of 25 tumor suppressor genes in bladder cancer using a methylation-specific (MS) multiplex ligation-de...

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Veröffentlicht in:	The Journal of molecular diagnostics : JMD 2011, Vol.13 (1), p.29-40
Hauptverfasser:	Cabello, Maria José, Grau, Laura, Franco, Noreli, Orenes, Esteban, Alvarez, Miguel, Blanca, Ana, Heredero, Oscar, Palacios, Alberto, Urrutia, Manuel, Fernández, Jesus María, López-Beltrán, Antonio, Sánchez-Carbayo, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biomarkers, Tumor - genetics Cell Line, Tumor DNA Methylation - genetics Female Genes, Tumor Suppressor Humans Ligase Chain Reaction Male Middle Aged Molecular Diagnostic Techniques Neoplasm Staging Pathology Regular Reproducibility of Results ROC Curve Sensitivity and Specificity Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology
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