Laminin-332-Rich Tumor Microenvironment for Tumor Invasion in the Interface Zone of Breast Cancer

Dense fibrosis, which is caused by desmoplastic reaction, is usually found in invasive ductal carcinoma and may represent the alteration of the tumor microenvironment preceding tumor invasion. Thus, the dense fibrotic zone around invasive ductal carcinoma can be considered to be the actual tissue si...

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Veröffentlicht in:	The American journal of pathology 2011, Vol.178 (1), p.373-381
Hauptverfasser:	Kim, Baek Gil, An, Hee Jung, Kang, Suki, Choi, Yoon Pyo, Gao, Ming-Qing, Park, Haengran, Cho, Nam Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast Neoplasms - genetics Breast Neoplasms - pathology Cadherins - genetics Cell Adhesion Molecules - genetics Epithelial Cells - metabolism Epithelial Cells - pathology Epithelial-Mesenchymal Transition - genetics Female Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Homeodomain Proteins - genetics Humans Integrin alpha6beta4 - genetics Investigative techniques, diagnostic techniques (general aspects) Kalinin Mammary gland diseases Matrix Metalloproteinase 14 - genetics Medical sciences MicroRNAs - genetics Myofibroblasts - metabolism Myofibroblasts - pathology Neoplasm Invasiveness Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Regular Snail Family Transcription Factors Transcription Factors - genetics Tumor Microenvironment Tumors Zinc Finger E-box-Binding Homeobox 1
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