Azole substituted oligonucleotides promote antiparallel triplex formation at non-homopurine duplex targets

The ability of certain azole substituted oligodeoxy-ribonucleotldes to promote antiparallel triple helix formation with duplex targets having CG or TA interruptions In the otherwise homopurine sequence was examined. 2-Deoxyribonucleosides of the azoles, which include pyrazole, imidazole, 1,2,4-triaz...

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Veröffentlicht in:	Nucleic acids research 1995-02, Vol.23 (4), p.647-653
Hauptverfasser:	Durland, Ross H., Rao, T. Sudhakar, Bodepudi, Veeraiah, Seth, Dale M., Jayaraman, Krishna, Revankar, Ganapathi R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Azoles - pharmacology Base Composition Base Sequence DNA - chemistry DNA - drug effects Macromolecular Substances Magnetic Resonance Spectroscopy Molecular Sequence Data Nucleic Acid Conformation - drug effects Oligodeoxyribonucleotides - chemical synthesis Oligodeoxyribonucleotides - pharmacology
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