Association of common KIBRA variants with episodic memory and AD risk

Abstract KIBRA single nucleotide polymorphism (SNP) rs17070145 was identified in a genome-wide association study (GWAS) of memory performance, with some but not all follow-up studies confirming association of its T allele with enhanced memory. This allele was associated with reduced Alzheimer's...

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Veröffentlicht in:	Neurobiology of aging 2011-03, Vol.32 (3), p.557.e1-557.e9
Hauptverfasser:	Burgess, Jeremy D, Pedraza, Otto, Graff-Radford, Neill R, Hirpa, Meron, Zou, Fanggeng, Miles, Richard, Nguyen, Thuy, Li, Ma, Lucas, John A, Ivnik, Robert J, Crook, Julia, Pankratz, V. Shane, Dickson, Dennis W, Petersen, Ronald C, Younkin, Steven G, Ertekin-Taner, Nilüfer
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - complications Alzheimer Disease - epidemiology Alzheimer Disease - genetics Alzheimer's disease Association studies in genetics Case control studies Episodic memory Female Gene expression Gene Frequency Genetic Predisposition to Disease Genome-Wide Association Study - methods Genotype Humans Internal Medicine Intracellular Signaling Peptides and Proteins KIBRA Male Mental Recall - physiology Meta-Analysis as Topic Middle Aged Neurology Neuropsychological Tests Phosphoproteins Polymorphism, Single Nucleotide - genetics Proteins - genetics Risk Factors United States - epidemiology
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