Genome-wide expression profile of first trimester villous and extravillous human trophoblast cells

Abstract We have examined the transcriptional changes associated with differentiation from villous to extravillous trophoblast using a whole genome microarray. Villous trophoblast (VT) is in contact with maternal blood and mediates nutrient exchange whereas extravillous trophoblast (EVT) invades the...

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Veröffentlicht in:	Placenta (Eastbourne) 2011-01, Vol.32 (1), p.33-43
Hauptverfasser:	Apps, R, Sharkey, A, Gardner, L, Male, V, Trotter, M, Miller, N, North, R, Founds, S, Moffett, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Case-Control Studies Cell Line, Tumor Cells, Cultured Chorionic Villi - metabolism Cluster Analysis Embryology: invertebrates and vertebrates. Teratology Female First trimester Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Regulatory Networks Genome, Human - physiology Humans Internal Medicine LAIR-2 Microarray Microarray Analysis Obstetrics and Gynecology Pre-Eclampsia - genetics Pre-Eclampsia - metabolism Pre-Eclampsia - pathology Pre-Eclampsia - urine Pregnancy Pregnancy Trimester, First - genetics Pregnancy Trimester, First - metabolism Trophoblast differentiation Trophoblasts - cytology Trophoblasts - metabolism Uterine NK cells
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