5-Aza-2′-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene

Sialyl Lewis X is a tumor-associated antigen frequently found in the advanced cancers. However, the mechanism for the production of this cancer antigen is not entirely clear. The objective of this study is to examine whether epigenetics is involved in the regulation of the formation of this antigen....

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Veröffentlicht in:The international journal of biochemistry & cell biology 2011-04, Vol.43 (4), p.586-593
Hauptverfasser: Chachadi, Vishwanath B., Cheng, Helen, Klinkebiel, David, Christman, Judith K., Cheng, Pi-Wan
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Sprache:eng
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