Dopamine regulation of Na+-K+-ATPase requires the PDZ-2 domain of sodium hydrogen regulatory factor-1 (NHERF-1) in opossum kidney cells

Na(+)-K(+)-ATPase activity in renal proximal tubule is regulated by several hormones including parathyroid hormone (PTH) and dopamine. The current experiments explore the role of Na(+)/H(+) exchanger regulatory factor 1 (NHERF-1) in dopamine-mediated regulation of Na(+)-K(+)-ATPase. We measured dopa...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2011-03, Vol.300 (3), p.C425-C434
Hauptverfasser:	Salyer, Sarah, Lesousky, Nina, Weinman, Edward J, Clark, Barbara J, Lederer, Eleanor D, Khundmiri, Syed J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Animals Cell Line, Transformed Cells Didelphis Dopamine Dopamine - pharmacology Dopamine - physiology Epithelial Cells - cytology Epithelial Cells - metabolism Hormones Humans Kidney Tubules, Proximal - cytology Kidney Tubules, Proximal - metabolism Kidneys Marsupials Membrane Transporters, Ion Channels and Pumps Mutation PDZ Domains - drug effects PDZ Domains - genetics PDZ Domains - physiology Phosphoproteins - chemistry Phosphoproteins - genetics Phosphoproteins - physiology Phosphorylation Protein Kinase C - metabolism Protein Subunits - metabolism Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - metabolism Retinoblastoma Protein - metabolism Sodium Sodium-Hydrogen Exchangers - chemistry Sodium-Hydrogen Exchangers - genetics Sodium-Hydrogen Exchangers - physiology Sodium-Potassium-Exchanging ATPase - metabolism T cell receptors
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