Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden

The transcription factor nuclear factor kappa B (NF-κB) is activated in human breast cancer tissues and cell lines. However, it is unclear whether NF-κB activation is a consequence of tumor formation or a contributor to tumor development. We developed a doxycycline-inducible mouse model, termed DNMP...

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Veröffentlicht in:	Oncogene 2010-11, Vol.30 (12), p.1402-1412
Hauptverfasser:	Connelly, Linda, Barham, Whitney, Onishko, Halina M., Sherrill, Taylor, Chodosh, Lewis A., Blackwell, Timothy S., Yull, Fiona E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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