Telavancin versus Vancomycin for Hospital-Acquired Pneumonia due to Gram-positive Pathogens

Background. Telavancin is a lipoglycopeptide bactericidal against gram-positive pathogens. Methods. Two methodologically identical, double-blind studies (0015 and 0019) were conducted involving patients with hospital-acquired pneumonia (HAP) due to gram-positive pathogens, particularly methicillin-r...

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Veröffentlicht in:	Clinical infectious diseases 2011-01, Vol.52 (1), p.31-40
Hauptverfasser:	Rubinstein, Ethan, Lalani, Tahaniyat, Corey, G. Ralph, Kanafani, Zeina A., Nannini, Esteban C., Rocha, Marcelo G., Rahav, Galia, Niederman, Michael S., Kollef, Marin H., Shorr, Andrew F., Lee, Patrick C., Lentnek, Arnold L., Luna, Carlos M., Fagon, Jean-Yves, Torres, Antoni, Kitt, Michael M., Genter, Fredric C., Barriere, Steven L., Friedland, H. David, Stryjewski, Martin E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Aminoglycosides - therapeutic use and Commentaries Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents ARTICLES AND COMMENTARIES Biological and medical sciences Cross Infection - drug therapy Cross Infection - microbiology Cultural groups Double-Blind Method Female General aspects Gram-positive bacteria Hospitals Human infectious diseases. Experimental studies and models Humans Infections Infectious diseases Lipoglycopeptides Male Medical cures Medical sciences Medications Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - isolation & purification Middle Aged Mortality Nosocomial infections Pathogens Pharmacology. Drug treatments Pneumology Pneumonia Pneumonia, Staphylococcal - drug therapy Pneumonia, Staphylococcal - microbiology Respiratory system : syndromes and miscellaneous diseases Staphylococcus aureus Staphylococcus infections Treatment Outcome Vancomycin - therapeutic use Ventilator associated pneumonia
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