The role of germline promoters and I exons in cytokine-induced gene-specific class switch recombination1

Germline transcription precedes class switch recombination. The promoter regions and I exons of these germline transcripts include binding site for activation- and cytokine-induced transcription factors, and the promoter regions/I exons are essential for class switch recombination. Therefore, it is...

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Veröffentlicht in:	The Journal of immunology (1950) 2010-12, Vol.186 (1), p.350-358
Hauptverfasser:	Dunnick, Wesley A., Shi, Jian, Holden, Victoria, Fontaine, Clinton, Collins, John T.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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