HLA-matched sibling bone marrow transplantation for β-thalassemia major

We describe outcomes after human leukocyte antigen-matched sibling bone marrow transplantation (BMT) for 179 patients with β-thalassemia major. The median age at transplantation was 7 years and the median follow-up was 6 years. The distribution of Pesaro risk class I, II, and III categories was 2%,...

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Veröffentlicht in:	Blood 2011-02, Vol.117 (5), p.1745-1750
Hauptverfasser:	Sabloff, Mitchell, Chandy, Mammen, Wang, Zhiwei, Logan, Brent R., Ghavamzadeh, Ardeshir, Li, Chi-Kong, Irfan, Syed Mohammad, Bredeson, Christopher N., Cowan, Morton J., Gale, Robert Peter, Hale, Gregory A., Horan, John, Hongeng, Suradej, Eapen, Mary, Walters, Mark C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemias. Hemoglobinopathies beta-Thalassemia - immunology beta-Thalassemia - therapy Biological and medical sciences Bone Marrow Transplantation Child Child, Preschool Diseases of red blood cells Female Graft Rejection Graft Survival Graft vs Host Disease Hematologic and hematopoietic diseases HLA Antigens - metabolism Humans International Agencies Male Medical sciences Siblings Survival Rate Tissue Donors Transplantation Transplantation, Homologous Treatment Outcome Young Adult
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