Decreased nitric oxide synthesis in rats with chronic renal failure

The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept for 6 weeks to induce CRF. On the experimental day, after measurement of arterial pressure under anesthesia, the arter...

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Veröffentlicht in:	Journal of Korean medical science 2000-08, Vol.15 (4), p.425-430
Hauptverfasser:	Kim, S W, Lee, J, Paek, Y W, Kang, D G, Choi, K C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - metabolism Enzyme Induction Isoenzymes - genetics Isoenzymes - metabolism Kidney - metabolism Kidney Failure, Chronic - metabolism Male Nephrectomy Nitrates - blood Nitrates - urine Nitric Oxide - biosynthesis Nitric Oxide - deficiency Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type II Nitric Oxide Synthase Type III Nitrites - blood Nitrites - urine Organ Specificity Rats Rats, Sprague-Dawley RNA, Messenger - biosynthesis
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