POEMS syndrome--a case report

POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI)...

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Veröffentlicht in:Journal of Korean medical science 1992-03, Vol.7 (1), p.79-84
Hauptverfasser: Kim, J W, Lee, S K, Ha, K M, Kim, K H, Joh, G Y, Kim, H J, Yang, S O, Hong, S H
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container_issue 1
container_start_page 79
container_title Journal of Korean medical science
container_volume 7
creator Kim, J W
Lee, S K
Ha, K M
Kim, K H
Joh, G Y
Kim, H J
Yang, S O
Hong, S H
description POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
doi_str_mv 10.3346/jkms.1992.7.1.79
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subjects Adult
Biopsy
Femur Neck - pathology
Humans
Magnetic Resonance Imaging
Male
Multiple Myeloma - complications
Multiple Myeloma - pathology
POEMS Syndrome - complications
POEMS Syndrome - diagnosis
title POEMS syndrome--a case report
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