Crystallization and preliminary X-ray crystallographic study of a methyltransferase involved in 2-methylisoborneol biosynthesis in Streptomyces lasaliensis

The biosynthetic pathway of the off‐flavour terpenoid alcohol 2‐methylisoborneol (2‐MIB) requires geranyl pyrophosphate methyltransferase (GPPMT) to methylate GPP before the cyclization reaction. GPPMT is the first example of an S‐adenosyl‐l‐methionine‐dependent methyltransferase that acts on genera...

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Veröffentlicht in:	Acta crystallographica. Section F, Structural biology and crystallization communications Structural biology and crystallization communications, 2011-03, Vol.67 (3), p.417-420
Hauptverfasser:	Ariyawutthiphan, Orapin, Ose, Toyoyuki, Tsuda, Muneya, Gao, YongGui, Yao, Min, Minami, Atsushi, Oikawa, Hideaki, Tanaka, Isao
Format:	Artikel
Sprache:	eng
Schlagworte:	2-methylisoborneol biosynthesis Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Bornanes - chemistry Bornanes - metabolism Crystallization Crystallization Communications Crystallography, X-Ray Crystals geranyl pyrophosphate methyltransferase Methyltransferases - chemistry Methyltransferases - genetics Methyltransferases - metabolism Molecular Sequence Data Molecular Structure Polyisoprenyl Phosphates - chemistry Polyisoprenyl Phosphates - metabolism Streptomyces - chemistry Streptomyces - enzymology Streptomyces lasaliensis
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