Hexapeptide Libraries for Enhanced Protein PTM Identification and Relative Abundance Profiling in Whole Human Saliva

Dynamic range compression (DRC) by hexapeptide libraries increases MS/MS-based identification of lower-abundance proteins in complex mixtures. However, two unanswered questions impede fully realizing DRC’s potential in shotgun proteomics. First, does DRC enhance identification of post-translationall...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of proteome research 2011-03, Vol.10 (3), p.1052-1061
Hauptverfasser:	Bandhakavi, Sricharan, Van Riper, Susan K, Tawfik, Pierre N, Stone, Matthew D, Haddad, Tufia, Rhodus, Nelson L, Carlis, John V, Griffin, Timothy J
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - chemistry Chromatography, High Pressure Liquid - methods Female Humans Isotope Labeling Male Peptide Library Peptides - analysis Protein Processing, Post-Translational Proteomics - methods Saliva - chemistry Tandem Mass Spectrometry - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!