Effect of ursodeoxycholic acid on experimental hepatic porphyria induced by griseofulvin

Griseofulvin(GF) has become the drug of choice as an antifungal agent for patients who suffer from many kinds of fungal infection. In order to clarify hepatic injury by griseofulvin(GF) overload and the effect of UDCA on GF-induced hepatic injury, the authors carried out biochemical, histologic, and...

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Veröffentlicht in:	Journal of Korean medical science 1991-06, Vol.6 (2), p.146-156
Hauptverfasser:	Choi, S W, Han, J H, Lim, K T, Cho, H M, Chung, K W, Sun, H S, Park, D H, Kim, B S, Seo, E J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Alkaline Phosphatase - blood Animals Bilirubin - blood Chemical and Drug Induced Liver Injury Griseofulvin - toxicity Liver Diseases - drug therapy Liver Diseases - pathology Mice Mice, Inbred ICR Microscopy, Electron Porphobilinogen - urine Porphyrias - chemically induced Porphyrias - drug therapy Porphyrias - pathology Ursodeoxycholic Acid - therapeutic use
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