Genome-wide functions of PML–RARα in acute promyelocytic leukaemia

PML—RAR (retinoic acid receptor) α is the hallmark protein of acute promyelocytic leukaemia, a highly malignant subtype of acute myeloid leukaemia that accounts for approximately 10% of all AML cases. Recently, several studies have been set out to obtain a comprehensive genome-wide view of the molec...

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Veröffentlicht in:	British journal of cancer 2011-02, Vol.104 (4), p.554-558
Hauptverfasser:	Saeed, S, Logie, C, Stunnenberg, H G, Martens, J H A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/176 631/80/86 692/699/67/1990/283/1897 Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Chromosome aberrations Drug Resistance Epidemiology Epigenesis, Genetic - physiology Genome, Human Humans Leukemia, Promyelocytic, Acute - genetics Medical genetics Medical sciences mini-review Minireview Models, Biological Molecular Medicine Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - physiology Oncology Signal Transduction - genetics Signal Transduction - physiology Tumors
Online-Zugang:	Volltext
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